The ticket, which expired at 4:45 p.m., was purchased at the BP gas station, located at 15500 Michigan Avenue in Dearborn.
Powerball tickets are valid for one year from the date of the drawing.
It was the second major Michigan Lottery draw game prize to go unclaimed this year. In May, a $105,000 Fantasy 5 jackpot went unclaimed.
The record for an unclaimed Lottery prize in Michigan is $34 million. It was set in 1998, when a winning Michigan Lotto game ticket, purchased at the Meijer located at 1350 West Lake Lansing Road in East Lansing, went unclaimed.